基因组学与动物遗传育种研究组 —— 代表性论文

(#为共同第一作者,*为通讯作者)
2018年度:

  • Xiao-Ju Hu, Ji Yang, Xing-Long Xie, Feng-Hua Lv, Yin-Hong Cao ,Wen-Rong Li, Ming-Jun Liu, Yu-Tao Wang, Jin-Quan Li, Yong-Gang Liu, Yan-Lin Ren, Zhi-Qiang Shen, Feng Wang, EEr Hehua, Jian-Lin Han, Meng-Hua Li* (2018) The genome landscape of Tibetan sheep reveals adaptive introgression from argali and the history of early human settlements on the Qinghai-Tibetan Plateau. Molecular Biology and Evolution (doi.org/10.1093/molbev/msy208)
  • Ji Yang(#), Xin Li(#), Yin-Hong Cao(#), Kisun Pokharel(#), Xiao-Ju Hu(#), Ze-Hui Chen(#), Song-Song Xu, Jaana Peippo, Mervi Honkatukia, Juha Kantanen, Meng-Hua Li* (2018)Comparative mRNAs and miRNAs expression in European mouflon (Ovis musimon) and sheep (Ovis aries) provide novel insights into the genetic mechanisms for female reproductive success. Heredity (doi: 10.1038/s41437-018-0090-1).
  • Lei Gao(#), Song-Song Xu(#), Jing-Quan Yang(#), Min Shen*, Meng-Hua Li* (2018) Genome-wide association study reveals novel genes for the ear size in sheep (Ovis aries)Animal Genetics 49:345-348.
  • Ze-Hui Chen(#), Min Zhang(#), Feng-Hua Lv(#), Xue Ren, Wen-Rong Li, Ming-Jun Liu, Kiwoong Nam, Michael W Bruford, Meng-Hua Li* (2018) Contrasting patterns of genomic diversity reveal accelerated genetic drift but reduced directional selection on X-chromosome in wild and domestic sheep species. Genome Biology and Evolution 10:1282-1297.
  • Song-Song Xu(#), Lei Gao(#), Xing-Long Xie, Yan-Ling Ren, Zhi-Qiang Shen, Feng Wang, Min Shen, Emma Eyporsdottir, Jon H. Hallsson,Tatyana Kiseleva, Juha Kantanen and Meng-Hua Li* (2018) Genome-wide association analyses highlight the potential for different genetic mechanisms for litter size among sheep breeds. Frontier in Genetics (Livestock genomics) 9:118.
  • Pokharel Kisun, Peippo Jaana, Honkatukia Mervi, Seppala Arja, Rautiainen Johanna, Ghanem Nasser, Hamama Tuula-Marjatta, Crowe Mark A, Andersson Magnus, Li Meng-Hua*, Kantanen Juha*(2018) Integrated ovarian mRNA and miRNA transcriptome profiling characterizes the genetic basis of prolificacy traits in sheep (Ovis aries) BMC Genomics 19:104.

2017年度:

  • Zhao Yong-Xin(#),Yang Ji(#), Lv Feng-Hua(#),Hu Xiao-Ju, Xie Xing-Long, Zhang Min, Li Wen-Rong, Liu Ming-Jun, Wang Yu-Tao, Li Jin-Quan, Liu Yong-Gang, Ren Yan-Ling, Wang Feng, Eer Hehua,  Kantanen, Juha Lenstra, Johannes Arjen, Han Jian-Lin, Li Meng-Hua* (2017) Genomic reconstruction of the history of native sheep reveals the peopling patterns of nomads and the expansion of early pastoralism in East Asia. Molecular Biology and Evolution 34:2380-2395.
  • Xu Song-Song#, Ren Xue#, Yang Guang-Li#, Xie Xing-Long, Zhao Yong-Xin, Zhang Min, Shen Zhi-Qiang, Ren Yan-Ling, Gao Lei, Shen Min, Juha Kantanen and Meng-Hua Li* (2017) Genome-wide association analysis identifies the genetic basis of fat deposition in the tails of sheep (Ovis aries) Animal Genetics 48:560-569.
  • Peng W. -F.(#), Xu S. -S.(#),Ren X.(#),Lv F. -H., Xie X. -L., Zhao  Y. -X., Zhang M., Shen Z. -Q., Ren Y. -L., Gao L.,Shen M., Kantanen J., Li M.-H.* (2017) A genome-wide association study reveals candidate genes for the supernumerary nipple phenotype in sheep (Ovis aries) Animal Genetics 48:570-579.
  • Xu Song-Song, Meng-Hua Li* (2017) Recent advances in understanding genetic variants associated with economically important traits in sheep (Ovis aries) revealed by high-throughput screening technologies. Frontiers of Agricultural Sciences and Engineering 4:279-288.

2016年度:

  • Ji Yang#, Wen-Rong Li#, Feng-Hua Lv#, San-Gang He#, Shi-Lin Tian#, Wei-Feng Peng, Ya-Wei Sun, Yong-Xin Zhao, Xiao-Long Tu, Min Zhang, Xing-Long Xie, Yu-Tao Wang, Jin-Quan Li, Yong-Gang Liu, Zhi-Qiang Shen, Feng Wang, Guang-Jian Liu, Hong-Feng Lu, Juha Kantanen, Jian-Lin Han, Meng-Hua Li* and Ming-Jun Liu*(2016)Whole-Genome Sequencing of Native Sheep Provides Insights into Rapid Adaptations to Extreme Environments. Molecular Biology and Evolution 33(10): 2576–2592.
    • 封面文章
    • 受到“International Livestock Research Institute (ILRI)”点评和报道
  • Ren X#. Yang GL#, Peng WF, Zhao YX, Zhang M, Chen ZH, Wu FA, Kantanen J, Shen M, Li M.-H.* (2016) A genome-wide association study identifies a genomic region for the polycerate phenotype in sheep (Ovis aries) Scientific Reports 6:201111.
  • Xiaoju Hu, Kisun Pokharel,Jaana Peippo, Nasser Ghanem, Ismael Zhaboyev, Juha Kantanen and Meng-Hua Li*. (2016)Identification and characterization of miRNAs in the ovaries of a highly prolific sheep breed. Animal Genetics 47:234-239.

2015年度:

  • Lv F-H, Peng W-F, Yang J, Zhao Y-X, Li W-R, Liu M-J, Ma Y-H, Zhao Q-J, Yang G-L, Wang F, Li J-Q, Liu Y-G, Shen Z-Q, Zhao S-G, Hehua E, Gorkhali NA, Farhad Vahidi SM, Muladno M, Naqvi AN, Tabell J, Iso-Touru T, Bruford MW, Kantanen J, Han J-L*, Li M-H* (2015). Mitogenomic Meta-Analysis Identifies Two Phases of Migration in the History of Eastern Eurasian Sheep. Molecular Biology and Evolution 32: 2515-2533.
    • 封面文章
    • 受到“Financial Times”,“Modern Farmer”和“ILRI”等媒体报道和点评
    • 受到《中国科学》的评述
    • 中国科学院科研进展英文评述
  • Jun Liu, Cuimin Wang, Dongli Fu, Xiaoju Hu, Xiangmo Xie, Pengfei Liu, Qiong Zhang and Meng-Hua Li* (2015) Phylogeography of Nanorana parkeri (Anura: Ranidae) on the Tibetan Plateau: effects of Plateau uplift and Quaternary climatic changes. Scientific Reports  5:9857
    • 中国科学院科研进展英文评述
  • Weimin Zhao, Yulian Mu, Lei Ma, Chen Wang, Zhonglin Tang, Shulin Yang, Rong Zhou, Xiaoju Hu, Meng-Hua Li* and Kui Li* (2015) Systematic identification and characterization of long intergenic non-coding RNAs in fetal porcine skeletal muscle development. Scientific Reports 5:8957.
  • Kisun Pokharel, Jaana Peippo, G?ran Andersson, Meng-Hua Li*, Juha Kantanen (2015) Transcriptome profiling of Finnsheep ovaries during out-of-season breeding period. Agricultural and Food Science 24: 1-9.
  • Kantanen J, L?vendahl P, Strandberg E, Eythorsdottir E, Li M.-H., Kettunen-Pr?bel A, Berg P, Meuwissen T. (2015) Utilization of farm animal genetic resources in a changing agro-ecological environment in the Nordic countries. Frontiers in Genetics 6:52.

2014年度:

  • Feng-Hua Lv, Saif Agha, Juha Kantanen, LiciaColli, Sylvie Stucki, James W. Kijas, Stéphane Joost, Meng-Hua Li*, Paolo Ajmone Marsan (2014) Adaptations to Climate-Mediated Selective Pressures in Sheep. Molecular Biology and Evolution31: 3324-3343.
    • 封面文章
    • 受到Science daily等媒体报道和点评
  • Ji Yang, Takahito Shikano, Meng-Hua Li*, Juha Meril? (2014) Genome-wide linkage disequilibrium in nine-spined stickleback. G3 – Genes Genomes Genetics4:1119-1129
  • Yang J, Li M.-H.* (2014) A multi-omics integrated study deciphers biology of the rumen and lipid metabolism. Science China Life Science 57: 951-953
    • 特邀评述
  • Liu J., T. Shikano, T. Leinonen, J. M. Cano, M.-H. Li*, J. Meril? (2014) Identification of major and minor QTL for ecologically important morphological traits in three-spined sticklebacks (Gasterosteus aculeatus). G3-Genes, Genomes, Genetics 4: 594-604
  • Shan L., Wu Q., Li Y., Shang H., Guo K., Wu J., Wei H., Zhao J., Yu J., Li M.-H.*(2014) Transcriptome profiling identifies differentially expressed genes in postnatal developing pituitary gland of miniature pig. DNA Research 21:207-216
  • Li M.-H.*, T. Tiirikka, J. Kantanen (2014) A genome-wide scan study identifies a single nucleotide substitution in ASIP associated with white versus non-white coat-colour variation in sheep (Ovisaries). Heredity 112: 122–131.
  • Zhang Min, Wei-Feng Peng, Guang-Li Yang, Feng-Hua Lv, Ming-Jun Liu, Wen-Rong Li, Yong-Gang Liu, Jin-Quan Li, Feng Wang, Zhi-Qiang Shen, Sheng-Guo Zhao, EEr Hehua, Nurbiy Marzanov, Maziek Murawski, Juha Kantanen and Meng-Hua Li (2014) Y chromosome haplotype diversity of domestic sheep (Ovis aries) in northern Eurasia. Animal Genetics 45:903-907.

2011-2013年度:

  • Wang C., Hu X., Xie X., Liu P., Meril? J., Zhang Q. *, Li M.-H.* (2013) Isolation and characterization of 113 polymorphic microsatellite loci for the Tibetan frog (Nanoranaparkeri) using next generation sequencing. Conservation Genetics Resources 5: 915-924.
  • Li M.-H., A.Osva, J. Kantanen (2012) Integrating multidisciplinary data for the conservation of livestock biodiversity: a case study of the Yakutian cattle in Siberia, the far east of Russia. Animal Genetics Resources 50:97-104.
  • Li M. H.* and J. Meril? (2011) Population differences in levels of linkage disequilibrium in the wild. Molecular Ecology 20: 2916-2928.
  • Li M.-H., I. Strandén, T. Tiirikka, M.-L. Sevón-Aimonen, J. Kantanen (2011) A comparison of approaches to estimate the inbreeding coefficient and pairwise relatedness using genomic and pedigree data in a sheep population. PLoS ONE 6: e26256.
  • Cano J.M., M.-H. Li, Laurila A, Vilkki J, Meril? J. (2011) First-generation linkage map for the common frog Ranatemporaria reveals sex linkage group.Heredity107: 530-536.
  • Li M.-H.*, J. Kantanen, A. Michelson, U. Saarma (2011) Genetic components of grey cattle in Estonia as revealed by microsatellite analysis using two Bayesian clustering methods. BMC Research Notes 4: 37.
  • Zerabruk M.#, Li M.-H. #, J. Kantanen, I. Olsaker, E. M. Ibeagha-Awemu, G. Erhardt, D. G. Bradley and O Vangen (2011) Genetic diversity and admixture of indigenous cattle breeds of North Ethiopia: implications to historical introgressions in the gateway region of cattle to Africa. Animal Genetics 43:257-266.
  • Nair A., S. Kumar, S. George, S. Gopalan, M.-H. Li, E. Leder and J. Meril? (2011) Sixty two new microsatellite markers for an endemic frog Indiranabeddomii from the Western Ghats biodiversity hotspot. Conservation Genetics Resources 3: 167-171.

2001-2010年度:

  • Tapio, I., Tapio, M., M.-H. Li, Popov, R., Ivanova, Z., Kantanen, J (2010) Estimation of relatedness among non-pedigreed Yakutiancryo-bank bulls using molecular data: implications for conservation and breed management. Genetics Selection Evolution 42: 9.
  • Li M. H.* and J. Meril? (2010) Genetic evidence for male-biased dispersal in the Siberian jay (Perisoreus infaustus) based on autosomal and Z chromosomal markers. Molecular Ecology 19: 5281-5295.
  • Li, M.H., Kantanen, J (2010) Genetic structure of Eurasian cattle (Bos taurus) based on microsatellites: clarification for their breed classification. Animal Genetics 41: 150-158.
  • Li, M.H., Iso-Touru, T., Lauren, H., Kantanen, J (2010) A microsatellite-based analysis for the detection of selection on BTA1 and BTA20 in northern Eurasian cattle (Bos taurus) populations. Genetics Selection Evolution 42: 14.
  • Li M. H.* and J. Meril? (2010) Avian Z-specific microsatellites map to pseudoautosomal or autosomal chromosomes in the Siberian jay (Perisoreus infaustus): insights into avian genome evolution from cross-species amplification tests. Journal of Genetics 89: 223-228.
  • Li M.-H.* and J. Meril?(2010) Sex-specific population structure, natural selection, and linkage disequilibrium in a wild bird population as revealed by genome-wide microsatellite analyses. BMC Evolutionary Biology 10: 66.
    • 受到 Science (328:19)“编辑的选择”栏目评述
  • Li M.-H.*, and J. Meril? (2010) Extensive linkage disequilibrium in a wild bird population. Heredity 104: 600-610.
  • Iso-Touru, T., J. Kantanen, M. H. Li, Z. Gizejewski and J.Vilkki (2009) Divergent evolution in cattle and pigs in the cytoplasmic domains of GHR and PRLR. BMC Evolutionary Biology 9:172.
  • Li M.-H.* K. V?lim?ki, M. Piha, T.Pakkala and J. Meril? (2009) Extrapair paternity and maternity in the three-toed woodpecker, Picoides tridactylus: insights from microsatellite-based parentage analysis. PLoS ONE 4: 1-6.
  • Li M.-H., I. Strandén, and J. Kantanen (2009) Genetic diversity and pedigree analysis of the Finnsheep breed. Journal of Animal Science 87:1598-1605.
  • Jarri S., M.-H. Li*, and J. Meril? (2009) A first-generation microsatellite-based genetic linkage map of the Siberian jay (Perisoreusinfaustus): insights into avian genome evolution. BMC Genomics 10: 1.
  • Agha S. H., F. Pilla, S. Galal, I. Shaat, M. D’Andrea, S. Reale, A. Z. A. Abdelsalam, and M.-H. Li (2008) Genetic diversity in Egyptian and Italian goat breeds measured with microsatellite polymorphism. Journal of Animal Breeding and Genetics 125: 194-200.
  • Li M.-H., I. Tapio, J. Vilkki, Z. Ivanova, T. Kiselyova, N. Marzanov, M. Cinkulov, S. Stojanovic, I. Ammosov, R. Popov, and J. Kantanen (2007) Genetic structure of cattle populations (Bostaurus) in northern Eurasia and the neighboring Near Eastern regions: implications for breeding strategies and conservation. Molecular Ecology 16:3839-3853.
    • 封面文章
  • Li M.-H., M. Zerabruk, O. Vangen, I. Olsaker, and J. Kantanen (2007) Reduced genetic structure of north Ethiopian cattle revealed by Y-chromosome analysis. Heredity 98: 214-221.
  • Li M.-H., T. Adamowicz, M. Switonski, I. Ammosov, Z. Ivanova, T. Kiselyova, R. Popov, and J. Kantanen (2006) Analysis of population differentiation in North Eurasian cattle (Bostaurus) using single nucleotide polymorphisms in three genes associated with production traits. Animal Genetics 37: 390-392.
  • Bennewitz J., J. Kantanen, I. Tapio, M.-H. Li, E. Kalm, J. Vilkki, I. Ammosov, Z. Ivanova, T. Kiselyova, R. Popov, and T. H. Meuwissen (2006) Estimation of breed contributions to present and future genetic diversity of 44 North Eurasian cattle breeds using core set diversity measures. Genetics Selection Evolution 38: 201-220.
  • Li M.-H., K. Li, J. Kantanen, Z. Feng, B. Fan, and S. H. Zhao (2006) Allelic variations in exon 2 of caprine MHC class II DRB3 gene in Chinese indigenous goats. Small Ruminant Research 66: 236-243.
  • Li M.-H., E. Nogovitsina, Z. Ivanova, G. Erhardt, J. Vilkki , R. Popov, I. Ammosov, T. Kiselyova, and J. Kantanen (2005) Genetic contributions of indigenous Yakutian cattle to two hybrid populations as revealed by microsatellite variation. Asian-Australasian Journal of Animal Sciences 18: 613-1619.
  • Li, M.-H., K. Sternbauer, P. T. Haahr, and J. Kantanen (2005) Genetic components in contemporary Faroe Islands Cattle as revealed as microsatellite analysis. Journal of Animal Breeding and Genetics 122: 309-317.
  • Li S. J., S. H, Yang, S. H. Zhao, B. Fan, M. Yu, H. S. Wang, M.-H. Li, B. Liu, T. A. Xiong, and K. Li (2004) Genetic diversity analyses of 10 indigenous Chinese pig populations based on 20 microsatellites. Journal of Animal Science 82:368-374.
  • Li M.-H., S, H. Zhao, and K. Li (2004) Diversity of Chinese indigenous goat breeds: a conservation perspective – a review. Asian-Australasian Journal of Animal Sciences 17: 726-732.
  • Mo D. L., B. Liu, Z. G. Wang, S. H. Zhao, M. Yu, B. Fan, M.-H. Li, T. A. Xiong, M. Yu, and K. Li (2003) Genetic variation and genetic relationship of seventeen Chinese indigenous pig breeds using ten serum protein loci. Asian-Australasian Journal of Animal Sciences 16: 939-945.
  • Yang S. L, Z. G Wang, B. Liu, G. X. Zhang, S. H. Zhao, M. Yu, B. Fan, M.-H. Li, and K. Li (2003) Genetic variation and relationships of eighteen Chinese indigenous pig breeds. Genetics Selection Evolution 35: 657-671.
  • Fan B., Z. G. Wang, Y. J. Li, X. L. Zhao, B. Liu, S. H. Zhao, M Yu, M.-H. Li, S. L. Chen, T.A. Xiong, and K. Li (2002) Genetic variation analysis within and among Chinese indigenous swine populations using microsatellite markers. Animal Genetics 33: 422-427.
  • Li M.-H., S. H. Zhao, C. Bian, H. S. Wang, H. Wei, B.Liu, M. Yu, B. Fan, S. L. Chen, M. J. Zhu, T. A. Xiong, and K. Li (2002) Genetic relationships among twelve indigenous Chinese goat populations based on microsatellite analysis. Genetics Selection Evolution 34: 729-744.
  • Chen S. L., M.-H. Li, Y. J. Li, S.H. Zhao, C. Z. Yu, M. Yu, B. Fan, T. A. Xiong, and K. Li (2001) RAPD variation and genetic distances among Tibetan, Inner Mongolia and Liaoning Cashmere goats. Asian-Australasian Journal of Animal Sciences 14: 1520-1522.
  • Sakha Ynaga. Cattle of the Yakuts (Granberg L., J. Kantanen& K. Soinieds). Finnish Academy of Science and Letters, Helsinki, Finland. 218 pp. (ISBN978-951-41-1032-0, Li M.-H.是该书的主要的编著者之一).